Therapeutic uses of botulinum toxin.
@article{Jankovic1991TherapeuticUO, title={Therapeutic uses of botulinum toxin.}, author={J. Jankovic and M. Brin}, journal={The New England journal of medicine}, year={1991}, volume={324 17}, pages={ 1186-94 } }
BOTULISM had been recognized by the 18th century, but the observation that a toxin produced by an anaerobic organism might be responsible for food poisoning was not made until 1897.1 Although seven immunologically distinct toxins have since been identified, only types A, B, and E have been linked to cases of botulism in humans.2 , 3 Botulinum toxin type A (hereafter referred to as botulinum toxin), one of the most lethal biologic toxins, has been found to be of therapeutic value in the… CONTINUE READING
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