Therapeutic uses of botulinum toxin.

@article{Jankovic1991TherapeuticUO,
  title={Therapeutic uses of botulinum toxin.},
  author={J. Jankovic and M. Brin},
  journal={The New England journal of medicine},
  year={1991},
  volume={324 17},
  pages={
          1186-94
        }
}
  • J. Jankovic, M. Brin
  • Published 1991
  • Medicine
  • The New England journal of medicine
  • BOTULISM had been recognized by the 18th century, but the observation that a toxin produced by an anaerobic organism might be responsible for food poisoning was not made until 1897.1 Although seven immunologically distinct toxins have since been identified, only types A, B, and E have been linked to cases of botulism in humans.2 , 3 Botulinum toxin type A (hereafter referred to as botulinum toxin), one of the most lethal biologic toxins, has been found to be of therapeutic value in the… CONTINUE READING
    747 Citations

    Topics from this paper

    Clinical use of botulinum neurotoxins.
    • 11
    Historical aspects of botulinum toxin
    • 140
    Botulinum toxins in neurological disease
    • 58
    • PDF
    Botulinum toxin and spasticity
    • 49
    • PDF
    Pharmacotherapy with Botulinum Toxin: Harnessing Nature's Most Potent Neurotoxin
    • 26
    Complications and adverse reactions with the use of botulinum toxin.
    • A. Klein
    • Medicine
    • Disease-a-month : DM
    • 2002
    • 70
    Complications and adverse reactions with the use of botulinum toxin.
    • A. Klein
    • Medicine
    • Seminars in cutaneous medicine and surgery
    • 2001
    • 64

    References

    SHOWING 1-10 OF 85 REFERENCES
    Experimental botulism in monkeys--a clinical pathological study.
    • 69
    Botulinum toxin treatment in spasmodic torticollis.
    • 109
    • PDF
    Negative antibody response to long-term treatment of facial spasm with botulinum toxin.
    • 36
    Systemic toxicity of botulinum toxin by intramuscular injection in the monkey
    • A. B. Scott, D. Suzuki
    • Medicine
    • Movement disorders : official journal of the Movement Disorder Society
    • 1988
    • 163
    Treatment of acquired nystagmus with botulinum A toxin.
    • 86