Therapeutic trials in 200 patients with HTLV-I-associated myelopathy/ tropical spastic paraparesis.

@article{Nakagawa1996TherapeuticTI,
  title={Therapeutic trials in 200 patients with HTLV-I-associated myelopathy/ tropical spastic paraparesis.},
  author={Masanori Nakagawa and Keiichi Nakahara and Yoichi Maruyama and Masato Kawabata and Itsuro Higuchi and Hiroaki Kubota and Shuji Izumo and Kimiyoshi Arimura and Mitsuhiro Osame},
  journal={Journal of neurovirology},
  year={1996},
  volume={2 5},
  pages={345-55}
}
We report here the results of therapeutic trials in 200 patients with HTLV-I-associated myelopathy (HAM)/tropical spastic paraparesis (TSP) conducted in our department between 1986 and 1993. Motor disability grades were improved by more than one grade in 69.5% (91/131) of patients by oral administration of prednisolone, 50% (3/6) by eperisone hydrochloride only, 43.8% (7/16) by blood purification (lymphocytapheresis and plasmapheresis), 40.0% (2/5) by intrathecal injection of hydrocortisone, 30… CONTINUE READING