Therapeutic targets to reduce cardiovascular disease in type 2 diabetes

@article{Desouza2009TherapeuticTT,
  title={Therapeutic targets to reduce cardiovascular disease in type 2 diabetes},
  author={Cyrus Desouza and Vivian Fonseca},
  journal={Nature Reviews Drug Discovery},
  year={2009},
  volume={8},
  pages={361-367}
}
The potential cardiovascular risks that are associated with drugs for type 2 diabetes have recently raised considerable clinical and regulatory concerns. As some risk factors for cardiovascular disease and type 2 diabetes are related, identifying agents that target shared underlying pathways and processes is an attractive therapeutic strategy. In this article, we review the background to and the implications of recent regulatory guidance on the development of new drugs for diabetes, and discuss… CONTINUE READING