Therapeutic targets for treating fibrotic kidney diseases.

Abstract

Renal fibrosis is the hallmark of virtually all progressive kidney diseases and strongly correlates with the deterioration of kidney function. The renin-angiotensin-aldosterone system blockade is central to the current treatment of patients with chronic kidney disease (CKD) for the renoprotective effects aimed to prevent or slow progression to end-stage… (More)
DOI: 10.1016/j.trsl.2014.07.010

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