Therapeutic targets for prevention and regression of progressive fibrosing renal diseases.

@article{Eitner2005TherapeuticTF,
  title={Therapeutic targets for prevention and regression of progressive fibrosing renal diseases.},
  author={Frank Eitner and Juergen Floege},
  journal={Current opinion in investigational drugs},
  year={2005},
  volume={6 3},
  pages={255-61}
}
Renal fibrosis complicates most chronic renal diseases, leading to a progressive loss of function and ultimately resulting in terminal renal failure. Molecular mechanisms underlying the development and progression of renal fibrosis have been increasingly identified, and much progress has been made towards a better understanding of the roles of different growth factors/cytokines and regulators of matrix turnover, as well as of the interactions between renal inflammation and fibrosis. This review… CONTINUE READING

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