Therapeutic targets for neuroblastomas.

  title={Therapeutic targets for neuroblastomas.},
  author={Garrett M. Brodeur and Radhika Iyer and Jamie L. Croucher and Tiangang Zhuang and Mayumi Higashi and Venkatadri Kolla},
  journal={Expert opinion on therapeutic targets},
  volume={18 3},
INTRODUCTION Neuroblastoma (NB) is the most common and deadly solid tumor in children. Despite recent improvements, the long-term outlook for high-risk NB is still < 50%. Further, there is considerable short- and long-term toxicity. More effective, less toxic therapy is needed, and the development of targeted therapies offers great promise. AREAS COVERED Relevant literature was reviewed to identify current and future therapeutic targets that are critical to malignant transformation and… CONTINUE READING
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