Therapeutic relevance of CD34 cell dose in blood cell transplantation for cancer therapy.

@article{Siena2000TherapeuticRO,
  title={Therapeutic relevance of CD34 cell dose in blood cell transplantation for cancer therapy.},
  author={Salvatore Siena and R Steven Schiavo and Paolo Pedrazzoli and Carmelo Carlo-Stella},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={2000},
  volume={18 6},
  pages={1360-77}
}
PURPOSE To review recent advances in peripheral-blood progenitor-cell (PBPC) transplantation in order to define the optimal cell dose required for autologous and allogeneic transplantation. MATERIALS AND METHODS A search of MEDLINE was conducted to identify relevant publications. Their bibliographies were also used to identify further articles and abstracts for critical review. RESULTS The CD34(+) cell content of a graft is regarded as an accurate predictor of engraftment success… CONTINUE READING