Therapeutic ratio of mono or combination bacterial lipopolysaccharide therapy in methylnitrosourea — induced rat mammary carcinoma

@article{Berger2004TherapeuticRO,
  title={Therapeutic ratio of mono or combination bacterial lipopolysaccharide therapy in methylnitrosourea — induced rat mammary carcinoma},
  author={M. Berger and E. Petru and D. Schm{\"a}hl},
  journal={Journal of Cancer Research and Clinical Oncology},
  year={2004},
  volume={113},
  pages={437-445}
}
SummaryFour experiments investigating the antitumor activity of bacterial lipopolysaccharide (LPS) against the autochthonous methylnitrosourea — induced mammary carcinoma are summarized. Administration of LPS alone i.v. caused distinct regression of small tumors following its first injection. This therapeutic effect, however, was short-lived and could not be maintained by administering a second dose. The observed antineoplastic activity of LPS was dose-related, whereas no dose-response… Expand
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