Therapeutic proteins: High affinity good, lower affinity better

Abstract

It’s always a bonus for researchers when apparently separate pathways for pathogenetic mechanisms in fact conveniently and neatly intertwine. A report by Stuart Lipton and colleagues in Science shows how two proposed mechanisms for nerve-cell death are intimately linked, and should therefore help to direct therapies aimed at treating neurological disorders… (More)
DOI: 10.1038/nrd923

Topics

Cite this paper

@article{Brazil2002TherapeuticPH, title={Therapeutic proteins: High affinity good, lower affinity better}, author={Melanie Brazil}, journal={Nature Reviews Drug Discovery}, year={2002}, volume={1}, pages={746-746} }