Therapeutic potentials of short interfering RNAs

  title={Therapeutic potentials of short interfering RNAs},
  author={Chit Tam and Jack Ho Wong and Randy Chi Fai Cheung and Tao Zuo and T. H. B. Ng},
  journal={Applied Microbiology and Biotechnology},
Short interfering RNA (siRNA) is one of the members of the family of RNA interference (RNAi). Coupled with the RNA-induced silencing complex (RISC), siRNA is able to trigger the cleavage of target RNAs which serve as a defensive system against pathogens. Meanwhile, siRNA in gene silencing opens a new avenue for the treatment of various diseases. SiRNA can effectively inhibit viral infection and replication and suppress tumorigenesis and various inflammation-associated diseases and… CONTINUE READING
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