Therapeutic potentials of gene silencing by RNA interference: principles, challenges, and new strategies.


During recent decades there have been remarkable advances in biology, in which one of the most important discoveries is RNA interference (RNAi). RNAi is a specific post-transcriptional regulatory pathway that can result in silencing gene functions. Efforts have been done to translate this new discovery into clinical applications for disease treatment… (More)
DOI: 10.1016/j.gene.2013.12.019


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