Therapeutic potential of peptide deformylase inhibitors.

  • D. Chen, Z. Yuan
  • Published 2005 in Expert opinion on investigational drugs


Peptide deformylase (PDF) is an attractive target for antibacterial drug discovery. Progress in the biological characterisation of the enzyme, coupled with newly obtained mechanistic and structural insight, enabled the pharmaceutical industry to discover potent PDF inhibitors that can be considered as clinical development candidates for this new class of… (More)


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