Therapeutic potential of metformin in papillary thyroid cancer in vitro and in vivo.

Abstract

Metformin, an anti-diabetic drug used in type 2 diabetes treatment, is reported to have oncopreventive or therapeutic roles in several human cancers. The present study investigated the therapeutic potential of physiologic dose of metformin in PTC. Metformin inhibited PTC cell viability and increased cell apoptosis in various doses (0.5-20mM) in BCPAP and… (More)
DOI: 10.1016/j.mce.2014.05.021

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