Therapeutic potential of human induced pluripotent stem cells in experimental stroke.

@article{Chang2013TherapeuticPO,
  title={Therapeutic potential of human induced pluripotent stem cells in experimental stroke.},
  author={Da-Jeong Chang and Nayeon Lee and In-Hyun Park and Chunggab Choi and Iksoo Jeon and Jihye Kwon and Seung-Hun Oh and Dong Ah Shin and Jeong Tae Do and Dong Ryul Lee and Hyunseung Lee and Hyeyoung Moon and Kwan Soo Hong and George Q. Daley and Jihwan Song},
  journal={Cell transplantation},
  year={2013},
  volume={22 8},
  pages={1427-40}
}
Ischemic stroke mainly caused by middle cerebral artery occlusion (MCAo) is a major type of stroke, but there are currently very limited therapeutic options for its cure. Neural stem cells (NSCs) or neural precursor cells (NPCs) derived from various sources are known to survive and improve neurological functions when they are engrafted in animal models of stroke. Induced pluripotent stem cells (iPSCs) generated from somatic cells of patients are novel cells that promise the autologous cell… CONTINUE READING
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