Therapeutic potential and functional interaction of carfilzomib and vorinostat in T-cell leukemia/lymphoma

@inproceedings{Gao2016TherapeuticPA,
  title={Therapeutic potential and functional interaction of carfilzomib and vorinostat in T-cell leukemia/lymphoma},
  author={Minjie Gao and Gege Chen and Houcai Wang and Bingqian Xie and Liangning Hu and Yuanyuan Kong and Guang Yang and Yi Tao and Ying Han and Xiaosong Wu and Yiwen Zhang and Bojie Dai and Jumei Shi},
  booktitle={Oncotarget},
  year={2016}
}
We previously showed that the proteasome inhibitor carfilzomib and the histone deacetylase inhibitor (HDACI) vorinostat cooperated to induce cell apoptosis in one T-cell leukemia cell line in vitro, implying the possibility of the combination treatment of carfilzomib and vorinostat as a potential therapeutic strategy in human T-cell leukemia/lymphoma. Here… CONTINUE READING