Therapeutic plasma exchange in two patients with stiff-person syndrome.

To the Editor: Stiff-person syndrome (SPS) is a rare disorder characterized by rigidity and painful spasms. Approximately 85% of patients have anti-glutamic acid decarboxylase-65 (anti-GAD65) with concurrent autoimmune disorders [1–3]. Along with corticosteroids, intravenous immunoglobulins (IVIG), and GABAergic agonists, therapeutic plasma exchange (TPE… CONTINUE READING