Therapeutic management of hypophosphatemic rickets from infancy to adulthood

@inproceedings{Linglart2014TherapeuticMO,
  title={Therapeutic management of hypophosphatemic rickets from infancy to adulthood},
  author={Agn{\`e}s Linglart and Martin Biosse-Duplan and Karine Briot and Catherine C. Chaussain and L. Esterle and S{\'e}verine Guillaume-Czitrom and Peter Kamenick{\'y} and J{\'e}r{\^o}me Nevoux and Dominique Pri{\'e} and Agn{\`e}s Rothenbuhler and Philippe R Wicart and Pol Harvengt},
  booktitle={Endocrine connections},
  year={2014}
}
In children, hypophosphatemic rickets (HR) is revealed by delayed walking, waddling gait, leg bowing, enlarged cartilages, bone pain, craniostenosis, spontaneous dental abscesses, and growth failure. If undiagnosed during childhood, patients with hypophosphatemia present with bone and/or joint pain, fractures, mineralization defects such as osteomalacia, entesopathy, severe dental anomalies, hearing loss, and fatigue. Healing rickets is the initial endpoint of treatment in children. Therapy… CONTINUE READING
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