Therapeutic intervention of Ebola virus infection in rhesus macaques with the MB-003 monoclonal antibody cocktail.

@article{Pettitt2013TherapeuticIO,
  title={Therapeutic intervention of Ebola virus infection in rhesus macaques with the MB-003 monoclonal antibody cocktail.},
  author={James Pettitt and Larry Zeitlin and Do H Kim and Cara Working and Joshua C Johnson and Ognian Bohorov and Barry Bratcher and Ernie Hiatt and Steven D. Hume and Ashley K. Johnson and Josh Morton and Michael H. Pauly and Kevin J. Whaley and Michael F. Ingram and Ashley M. Zovanyi and Megan L. Heinrich and Ashley E. Piper and Justine M Zelko and Gene Garrard Olinger},
  journal={Science translational medicine},
  year={2013},
  volume={5 199},
  pages={199ra113}
}
Ebola virus (EBOV) remains one of the most lethal transmissible infections and is responsible for high fatality rates and substantial morbidity during sporadic outbreaks. With increasing human incursions into endemic regions and the reported possibility of airborne transmission, EBOV is a high-priority public health threat for which no preventive or therapeutic options are currently available. Recent studies have demonstrated that cocktails of monoclonal antibodies are effective at preventing… CONTINUE READING