Therapeutic insulins and their large-scale manufacture

@article{Walsh2004TherapeuticIA,
  title={Therapeutic insulins and their large-scale manufacture},
  author={G. Walsh},
  journal={Applied Microbiology and Biotechnology},
  year={2004},
  volume={67},
  pages={151-159}
}
  • G. Walsh
  • Published 2004
  • Medicine
  • Applied Microbiology and Biotechnology
  • Biotechnological innovations over the past 25 years have underpinned the rapid development of a thriving biopharmaceutical sector. Therapeutic insulin remains one of the most commonly used products of pharmaceutical biotechnology and insulin-based products command annual global sales in excess of $4.5 billion. Innovations in its method of production and in particular the advent of engineered insulin analogues provide a fascinating insight into how scientific and technological advances have… CONTINUE READING
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    References

    SHOWING 1-10 OF 61 REFERENCES
    Insulin therapies - past, present and future.
    • 88
    Monomeric insulins obtained by protein engineering and their medical implications
    • 438
    • Highly Influential
    Research, Development, Production, and Safety of Biosynthetic Human Insulin
    • 66
    Insulins today and beyond
    • 309
    • Highly Influential
    Closed-loop insulin delivery-the path to physiological glucose control.
    • 283
    Insulin Lispro (Humalog)
    • 13
    Alternative routes of insulin delivery
    • 317
    New Developments in Insulin Delivery
    • 32
    Oral insulin delivery.
    • 250