Therapeutic implications of hepatitis B virus genotypes.

  title={Therapeutic implications of hepatitis B virus genotypes.},
  author={Chun-Jen Liu and Jia-Horng Kao and D. -S. Chen},
  journal={Liver international : official journal of the International Association for the Study of the Liver},
  volume={25 6},
BACKGROUND/AIMS Hepatitis B virus (HBV) is a global health problem. In addition to the implementation of universal hepatitis B vaccination, effective and individualized treatment of chronic hepatitis B to prevent progression into end-stage liver diseases and hepatocellular carcinoma is still needed. HBV has been designated eight genotypes (A-H) based on genome sequence divergence. The epidemiology of HBV genotypes and their implications on the responses to antiviral therapy have become… CONTINUE READING
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