Therapeutic immunization with dendritic cells loaded with heat-inactivated autologous HIV-1 in patients with chronic HIV-1 infection.

@article{Garca2005TherapeuticIW,
  title={Therapeutic immunization with dendritic cells loaded with heat-inactivated autologous HIV-1 in patients with chronic HIV-1 infection.},
  author={F. J. Mendez Garc{\'i}a and Merylene Lejeune and N{\'u}ria Climent and C. Redondo Gil and Jos{\'e} Alcam{\'i} and Vanessa Morente and Lluc{\`i}a Alos and Alba Valdivia Ruiz and Javier Setoain and E. Quijada Fumero and Pedro Filipe Martins de Castro and Anna L{\'o}pez and Anna Cruceta and Carlos Piera and Eric Florence and Arturo Pereira and Agn{\`e}s Libois and Nuria Gonz{\'a}lez and Meritxell Guil{\'a} and Miguel Caballero and Francisco Lome{\~n}a and Joan Joseph and Jos{\'e} Ma Mir{\'o} and Tom{\'a}s Pumarola and Montserrat Plana and Jose M. Gatell and Teresa Gallart},
  journal={The Journal of infectious diseases},
  year={2005},
  volume={191 10},
  pages={1680-5}
}
Therapeutic immunization with autologous monocyte-derived dendritic cells (DCs) loaded with heat-inactivated autologous human immunodeficiency virus type 1 (HIV-1) in 12 patients with chronic HIV-1 infection who were receiving highly active antiretroviral therapy (HAART) was feasible, safe, and well tolerated. Virus was obtained during an initial interruption of HAART (hereafter, "stop 1") so that DCs could be pulsed. After immunization and a second interruption of HAART (hereafter, "stop 2… CONTINUE READING

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