Therapeutic immune reconstitution in HIV-1-infected children is independent of their age and pretreatment immune status.

@article{Rossum2001TherapeuticIR,
  title={Therapeutic immune reconstitution in HIV-1-infected children is independent of their age and pretreatment immune status.},
  author={Annemarie van Rossum and Henri{\"e}tte J. Scherpbier and Ellen G van Lochem and Nadine G. Pakker and Walentina A. T. Slieker and Katja C. Wolthers and Marijke T. L. Roos and Jac H Kuijpers and Herbert Hooijkaas and Nico G. Hartwig and Sybil P Geelen and Tom F. W. Wolfs and Joep M. A. Lange and Frank A Miedema and Ronald de Groot},
  journal={AIDS},
  year={2001},
  volume={15 17},
  pages={2267-75}
}
OBJECTIVE To evaluate long-term immune reconstitution of children treated with highly active antiretroviral therapy (HAART). METHODS The long-term immunological response to HAART was studied in 71 HIV-1-infected children (aged 1 month to 18 years) in two prospective, open, uncontrolled national multicentre studies. Blood samples were taken before and after HAART was initiated, with a follow-up of 96 weeks, and peripheral CD4 and CD8 T cells plus naive and memory subsets were identified in… CONTINUE READING