Therapeutic hypothermia attenuates liver injury in polymicrobial sepsis model of rats via Akt survival pathway.

Abstract

BACKGROUND Therapeutic hypothermia has been proposed to protect organs in some diseases. However, the effect of therapeutic hypothermia on liver injury in sepsis is unknown. The aim of this study was to evaluate the effects of therapeutic hypothermia on liver injury in sepsis. METHODS Male Sprague-Dawley rats underwent cecal ligation and incision (CLI… (More)
DOI: 10.1016/j.jss.2012.05.045

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