Therapeutic hypothermia after cardiac arrest

@article{Holzer2005TherapeuticHA,
  title={Therapeutic hypothermia after cardiac arrest},
  author={Michael Holzer and Wilhelm Behringer},
  journal={Current Opinion in Anaesthesiology},
  year={2005},
  volume={18},
  pages={163–168}
}
Purpose of review Most patients who suffer a cardiac arrest die after the event. Full neurological recovery occurs in only 6–23%. Until recently no specific post-arrest therapy was available to improve outcome. Application of therapeutic hypothermia (32–34°C for 12–24 h) applied after cardiac arrest could help to improve this dreadful situation. This review covers the background of and recent clinical studies into hypothermia after cardiac arrest, and gives some insights into the future of… Expand
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TLDR
In patients who have been successfully resuscitated after cardiac arrest due to ventricular fibrillation, therapeutic mild hypothermia increased the rate of a favorable neurologic outcome and reduced mortality. Expand
Intra-Arrest Cooling Improves Outcomes in a Murine Cardiac Arrest Model
TLDR
Timing of hypothermia is a crucial determinant of survival in the murine arrest model, and early intra-arrest cooling appears to be significantly better than delayed post-ROSC cooling or normothermic resuscitation. Expand
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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