Therapeutic exploitation of apoptosis and autophagy for glioblastoma.


Induction of caspase-dependent apoptosis (type I cell death) is a major mechanism by which most chemotherapeutic drugs and radiation kill tumor cells. However, conventional cancer therapies fail to mediate their effects in a target-specific fashion. The extremely unfavorable prognosis for patients suffering from glioblastomas (GBMs) is strongly correlated… (More)


Cite this paper

@article{Kgel2010TherapeuticEO, title={Therapeutic exploitation of apoptosis and autophagy for glioblastoma.}, author={Donat K{\"o}gel and Simone Fulda and Michel Mittelbronn}, journal={Anti-cancer agents in medicinal chemistry}, year={2010}, volume={10 6}, pages={438-49} }