Therapeutic efficacy of legalon and lokhein with respect to experimental Reye's syndrome

  title={Therapeutic efficacy of legalon and lokhein with respect to experimental Reye's syndrome},
  author={A. I. Vengerovskii and I. Sukhodolo and V. Chuchalin and A. Arbuzov and M. B. Chervyakova and Yu. Yu. Mel'nik and E. Grishina and A. Saratikov},
  journal={Pharmaceutical Chemistry Journal},
  • A. I. Vengerovskii, I. Sukhodolo, +5 authors A. Saratikov
  • Published 2006
  • Chemistry
  • Pharmaceutical Chemistry Journal
  • Hepatoprotectors are known to exhibit therapeutic efficacy with respect to hepatitis and cirrhosis caused "by hepatotropic toxic substances [1, 2]. It is possible to extend the list of indications for the use of hepatoprotectors by including Reye's syndrome (RS)a serious complication accompanying the acetylsalicylic acid therapy of children with viral infections such as type B influenza and varicella [3, 4]. RS appears as a result of carnitine deficiency and the toxic effects of salicylates and… CONTINUE READING

    Figures and Tables from this paper


    Reye's Syndrome
    • 10
    Clinical pharmacology of hepatoprotectors
    • 3
    Okhrimovich, Clini- cal Pharmacology of Hepatoprotectors [in Russian
    • 1995
    Kamyshnikov, A Handbook on Clinical Chemistry [in Russian], Belarus
    • Minsk
    • 1982
    Schiebler, Enzyme Histochemistry
    • A Laboratory Manual,
    • 1979
    A . S . Saratikov and A . I . Vengerovskii , Eksp
    • Biochim . Biophys . Acta