Therapeutic effects of propolis essential oil on anxiety of restraint-stressed mice.

@article{Li2012TherapeuticEO,
  title={Therapeutic effects of propolis essential oil on anxiety of restraint-stressed mice.},
  author={Y Li and H-Z Xuan and Q-Y Shou and Z-G Zhan and Xiaoguang Lu and Fuliang Hu},
  journal={Human & experimental toxicology},
  year={2012},
  volume={31 2},
  pages={157-65}
}
Propolis has a broad spectrum of biological activities; however, whether its essential oils have neuroprotective effects is unknown. In this study, we found that propolis essential oil (PEO) could significantly reverse the anxiety-like behavior of restraint-stressed mice, and has no effect on locomotor activity. Furthermore, PEO significantly decreased the plasma levels of cortisol (CORT), adrenocorticotropic hormone (ACTH) and malondialdehyde (MDA), whereas it increased the activity of… CONTINUE READING