Therapeutic effects of naringin in a guinea pig model of ovalbumin-induced cough-variant asthma.

  title={Therapeutic effects of naringin in a guinea pig model of ovalbumin-induced cough-variant asthma.},
  author={Hao-yan Jiao and W. Su and Peibo Li and Y. Liao and Q. Zhou and N. Zhu and Li-li He},
  journal={Pulmonary pharmacology & therapeutics},
  • Hao-yan Jiao, W. Su, +4 authors Li-li He
  • Published 2015
  • Medicine
  • Pulmonary pharmacology & therapeutics
  • Naringin, a well known component isolated from Exocarpium Citri Grandis, has significant antitussive effects. Recently, Naringin exhibited novel anti-inflammatory effect in chronic inflammatory diseases. In this work, we firstly evaluated the effects of naringin on enhanced cough, airway hyper-responsiveness (AHR), and airway inflammation in an ovalbumin-induced experimental cough-variant asthma (CVA) model in guinea pigs. We investigated the effect of naringin (18.4 mg/kg, per os, single dose… CONTINUE READING
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