Therapeutic effects of IGF-1 on stress urinary incontinence in rats with simulated childbirth trauma.


PURPOSE We examined the effect of IGF-1 in a rat model of stress urinary incontinence induced by simulated childbirth trauma. MATERIALS AND METHODS Simulated birth trauma was induced by vaginal distension in female Sprague Dawley® rats. Four, 7, 14 and 28 days after distension we performed functional assessment by measuring leak point pressure, urethral… (More)
DOI: 10.1016/j.juro.2013.08.109


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