Therapeutic effect of ghrelin in the course of cerulein-induced acute pancreatitis in rats.

@article{Warzecha2010TherapeuticEO,
  title={Therapeutic effect of ghrelin in the course of cerulein-induced acute pancreatitis in rats.},
  author={Zygmunt Warzecha and Piotr Ceranowicz and Artur Dembiński and Jakub Cieszkowski and Beata Kuśnierz-Cabala and Romana A Tomaszewska and Atsukazu Kuwahara and Ikuo Kato},
  journal={Journal of physiology and pharmacology : an official journal of the Polish Physiological Society},
  year={2010},
  volume={61 4},
  pages={419-27}
}
Recent studies have shown that pretreatment with ghrelin exhibits protective effect in the gut. Administration of ghrelin reduces gastric mucosal damage, as well as inhibits the development of experimental pancreatitis. However, this protective effect requires administration of ghrelin before gastric or pancreatic damage and thus has a limited clinical value. The aim of present study was to assess the influence of ghrelin administered after development of acute pancreatitis on the course of… CONTINUE READING
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