Therapeutic effect of doxycycline in experimental subclinical canine monocytic ehrlichiosis: evaluation of a 6-week course.

@article{Harrus1998TherapeuticEO,
  title={Therapeutic effect of doxycycline in experimental subclinical canine monocytic ehrlichiosis: evaluation of a 6-week course.},
  author={Shimon Harrus and Trevor Waner and Itzhak Aizenberg and Hylton Bark},
  journal={Journal of clinical microbiology},
  year={1998},
  volume={36 7},
  pages={2140-2}
}
The efficacy of doxycycline treatment (10 mg/kg of body weight every 24 h for 42 days) in eliminating Ehrlichia canis from four subclinically infected dogs was evaluated. One dog remained PCR positive, suggesting that 6 weeks of doxycycline treatment may not be sufficient to clear E. canis parasites from all subclinically infected dogs. Serology (indirect immunofluorescent antibody assay) was shown to be unreliable in assessing recovery from the carrier state, as anti-E. canis antibodies… CONTINUE READING