Therapeutic effect of Berenil and Samorin in mice infected with four trypanosome populations isolated from Zambian cattle.

@article{Chitambo1991TherapeuticEO,
  title={Therapeutic effect of Berenil and Samorin in mice infected with four trypanosome populations isolated from Zambian cattle.},
  author={Harrison Chitambo and Akira Arakawa},
  journal={Veterinary parasitology},
  year={1991},
  volume={39 1-2},
  pages={
          43-52
        }
}
Four populations of Trypanosoma congolense and Trypanosoma brucei brucei were isolated from cattle under different management practices and environments in Zambia. All four isolates had varied responses to both diminazene aceturate (Berenil) and isometamidium chloride (Samorin) as curative drugs in infected mice. Trypanosomes from a traditionally managed herd in a high-tsetse-challenge area had the strains most resistant to Berenil, with maximum curative dose of 45 mg kg-1 body weight. Another… CONTINUE READING