Therapeutic drug monitoring principles in the neonate. National Academy of CLinical Biochemistry.

Abstract

Therapeutic drug monitoring in the newborn infant is necessary because dose requirements differ greatly from those for older children. These differences stem from major changes in kinetic disposition at the absorption, distribution, and elimination phases. The small blood volume of neonates makes them sensitive to iatrogenic blood loss. Similarly, the small… (More)

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@article{Koren1997TherapeuticDM, title={Therapeutic drug monitoring principles in the neonate. National Academy of CLinical Biochemistry.}, author={G. 215 Sapir - Koren}, journal={Clinical chemistry}, year={1997}, volume={43 1}, pages={222-7} }