Therapeutic drug monitoring of posaconazole in hematology adults under posaconazole prophylaxis: influence of food intake

@article{Eiden2011TherapeuticDM,
  title={Therapeutic drug monitoring of posaconazole in hematology adults under posaconazole prophylaxis: influence of food intake},
  author={Collin Eiden and J. C. Meniane and H{\'e}l{\`e}ne Peyri{\`e}re and Sabrina Eymard-Duvernay and G{\'e}raud Le Falher and Patrice C{\'e}ballos and Nathalie Fegueux and Maryl{\`e}ne Cociglio and J. Reynes and Dominique Hillaire-Buys},
  journal={European Journal of Clinical Microbiology & Infectious Diseases},
  year={2011},
  volume={31},
  pages={161-167}
}
Posaconazole (PCZ) is given at 200 mg three times daily as a fungal prophylaxis in neutropenic hematologic malignancy patients. A relationship between exposure, plasma concentration, and efficacy is suggested. The objectives of this prospective study were to analyze the PCZ plasma concentration in hematology adults at high risk of developing invasive fungal infections (IFIs), and factors that could have an impact on the PCZ plasma concentration. PCZ plasma concentrations were measured after 2… CONTINUE READING

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evaluation of 18 controlled studies in healthy volunteers

  • A Moton, G Krishna, Wang Z Tolerability, safety profile of posaconazole
  • J Clin Pharm Ther 34:301–311 Eur J Clin…
  • 2012
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