Therapeutic drug monitoring in HIV infection: current status and future directions.

@article{Back2002TherapeuticDM,
  title={Therapeutic drug monitoring in HIV infection: current status and future directions.},
  author={David J. Back and Giorgio Gatti and Courtney Fletcher and Rodolphe Garaffo and Richard Haubrich and Richard M. W. Hoetelmans and Michael Kurowski and Andrew D Luber and Concepta Merry and Carlo Federico Perno},
  journal={AIDS},
  year={2002},
  volume={16 Suppl 1},
  pages={S5-37}
}
BACKGROUND Highly active antiretroviral therapy (HAART) can suppress viral replication and prolong patient life substantially. However, HAART can fail for a number of reasons, including incomplete adherence, pharmacokinetic factors and the emergence of resistance. Because the number of possible antiretroviral combinations is limited, the use of existing treatment options must be optimized. Whether the application of therapeutic drug monitoring (TDM) in routine clinical practice may help with… CONTINUE READING