Therapeutic complement inhibition: new developments.

  title={Therapeutic complement inhibition: new developments.},
  author={Woodruff Emlen and Wenhan Li and Michael Kirschfink},
  journal={Seminars in thrombosis and hemostasis},
  volume={36 6},
Activation of the complement system significantly contributes to the pathogenesis of various acute and chronic inflammatory diseases. Current strategies to inhibit complement include the replacement or substitution of endogenous soluble complement inhibitors (e.g., C1 inhibitor [C1 inh], recombinant soluble complement receptor 1, TP10), the administration… CONTINUE READING