Therapeutic approaches for the delivery of TNF-α siRNA.

  title={Therapeutic approaches for the delivery of TNF-α siRNA.},
  author={Palpandi Pandi and Anjali Jain and Saka Raju and Wahid Ali Khan},
  journal={Therapeutic delivery},
  volume={8 5},
Immune-mediated diseases are emerging as a major healthcare concern in the present era. TNF-α, a proinflammatory cytokine, plays a major role in the manifestation of these diseases by mediating different pathways and inducing the expression of other cytokines. In last decades, monoclonal antibodies and extracellular portion of human TNF-α receptors are… CONTINUE READING