Therapeutic antibodies: successes, limitations and hopes for the future.

@article{Chames2009TherapeuticAS,
  title={Therapeutic antibodies: successes, limitations and hopes for the future.},
  author={Patrick Chames and Marc H. V. van Regenmortel and Etienne Weiss and Daniel Baty},
  journal={British journal of pharmacology},
  year={2009},
  volume={157 2},
  pages={
          220-33
        }
}
With more than 20 molecules in clinical use, monoclonal antibodies have finally come of age as therapeutics, generating a market value of $11 billion in 2004, expected to reach $26 billion by 2010. While delivering interesting results in the treatment of several major diseases including autoimmune, cardiovascular and infectious diseases, cancer and inflammation, clinical trials and research are generating a wealth of useful information, for instance about associations of clinical responses with… CONTINUE READING

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