• Corpus ID: 78757766

Therapeutic and safety evaluation of curcumin's antimicrobial and anti-inflammatory properties in canine and equine

@inproceedings{Bland2016TherapeuticAS,
  title={Therapeutic and safety evaluation of curcumin's antimicrobial and anti-inflammatory properties in canine and equine},
  author={Stephanie D. Bland},
  year={2016}
}

• S. Bland
• Published 2016
• Biology, Medicine

The objective of this investigation was to evaluate the efficacy and safety of 95% curcumin and 95% liposomal-curcumin in moderately arthritic dogs. Ten client-owned dogs in a randomized, double-blinded study received either 95% curcumin (500 mg) once a day (SID) or 95% curcumin (250 mg) twice a day (BID) for a period of five months. Dogs were evaluated each month for physical condition (body weight, body temperature, heart rate, and respiratory rate), pain associated with arthritis (overall pain, pain from limb manipulation, and pain after physical exertion), and range of motion was measured using a goniometer on the stifle, shoulder, and elbow joints. Serum samples collected from these dogs were examined each month for biomarkers of liver (total bilirubin, ALT, and AST), kidney (BUN and creatinine), heart and muscle (creatine kinase) functions. The findings of this study revealed that dogs receiving 95% curcumin (Group-I) and 95% liposomal-curcumin had a significant (P 0.05) in physical parameters or serum markers, suggesting that both 95% curcumin and 95% liposomal-curcumin were well tolerated by moderately arthritic dogs. It was concluded that both