Therapeutic alternatives in cutaneous T-cell lymphoma.

  title={Therapeutic alternatives in cutaneous T-cell lymphoma.},
  author={Kenneth Holloway and Franklin P Flowers and Francisco A Ramos-Caro},
  journal={Journal of the American Academy of Dermatology},
  volume={27 3},
Mycosis fungoides and Sézary syndrome, collectively referred to as cutaneous T-cell lymphoma, are non-Hodgkin's lymphomas that initially appear in the skin. Early-stage disease, limited to the skin, is best treated with sequential topical therapies such as topical nitrogen mustard, psoralen phototherapy (PUVA), or total-skin electron beam therapy. Photopheresis is the first line of therapy for the patient with erythroderma. Systemic therapy is generally reserved for patients with refractory… CONTINUE READING