Therapeutic Trials in Acute Gouty Arthritis

@article{Levin1956TherapeuticTI,
  title={Therapeutic Trials in Acute Gouty Arthritis},
  author={M. H. Levin and S. Marcus and D. Strange and R. Swezey},
  journal={Annals of the Rheumatic Diseases},
  year={1956},
  volume={15},
  pages={233 - 236}
}
Colchicine remains the agent of choice in the treatment of acute gouty arthritis. In recent years valuable additions to the therapeutic armamentarium in this disease include ACTH, cortisone, hydrocortisone acetate, prednisone, and Butazolidin (Wolfson, Hunt, Cohn, Robinson, and Duff, 1950; Gutman and Yu, 1950, 1952; Freyberg, 1955; Hartung, 1955; Steinbrocker, Neustadt, and Ehrlich, 1954). All of these are effective systemically, and in addition hydrocortisone acetate appears beneficial when… Expand
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Topics from this paper

Treatment of acute gouty arthritis with demecolcine.
TLDR
Skin rash, depilation, and bone marrow depression, manifested by leukopenia, thromb openia, and anemia, have occurred in patients with chronic myelogenous leukemia and other neoplastic diseases, and the chemical similarity of demecolcine and colchicine was decided to observe its effect in patients. Expand
Hematologic toxicity after the use of desacetylmethylcolchicine in the treatment of gouty arthritis.
TLDR
Recent reports have indicated that because of the rarity of gastrointestinal toxicity, Colcemide might be a more useful agent than colchicine and indeed might even replace it in the management of acute gouty arthritis. Expand
Effect of desacetylmethylcolchicine (Colcemide) in acute gouty arthritis
TLDR
Although gastrointestinal symptoms were avoided, other more serious undesirable effects such as bone-marrow depression and alopecia are cited. Expand
Demecolcine toxicity: a case report of severe hematopoietic toxicity and a review of the literature.
TLDR
A patient with acute gouty arthritis, in whom multiple toxic effects resulted from demecolcine treatment, is described, with specific reference to the hematopoietic system. Expand
Acute gouty arthritis provoked by cerebrovascular disease.
Colchicine. Clinical pharmacology in acute gouty arthritis.
  • S. Wallace
  • Medicine
  • The American journal of medicine
  • 1961

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