Therapeutic Synergism of Tiazofurin and Selected Antitumor Drugs against Sensitive and Resistant P388 Leukemia in Mice1


Tiazofurin is a synthetic "( " nucleoside analogue with a promising spectrum of experimental antitumor activity and a relatively novel mech anism of action. Previous work in our laboratories had revealed indica tions of collateral sensitivity and therapeutic synergism for selected murine tumor models treated with tiazofurin alone or in combination with an… (More)


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