Therapeutic Strategies for Laryngeal Manifestations of Gastroesophageal Reflux Disease

@article{Yuksel2013TherapeuticSF,
  title={Therapeutic Strategies for Laryngeal Manifestations of Gastroesophageal Reflux Disease},
  author={Elif Saritas Yuksel and Michael Fredrick Vaezi},
  journal={Journal of Clinical Gastroenterology},
  year={2013},
  volume={47},
  pages={195–204}
}
  • E. YukselM. Vaezi
  • Published 1 March 2013
  • Medicine
  • Journal of Clinical Gastroenterology
Gastroesophageal reflux disease is increasingly associated with ear, nose, and throat symptoms, including laryngitis. Many patients are unaware of the gastroesophageal etiology of their symptoms. A variety of criteria are used to diagnose this condition, including laryngoscopy, esophagogastroduodenoscopy, and the use of ambulatory pH and impedance monitoring. However, no test serves as the gold standard for the diagnosis given their lack of sensitivity and specificity for reflux disease… 

Supraesophageal Reflux Disease (SERD)

Supraesophareal reflux disease is a form of acid reflux manifested not by heartburn but rather by respiratory or laryngeal symptoms, and the nonspecific nature of the symptoms and the difficulty in diagnosis it is accepted that failure of a properly administered therapeutic trial should prompt further investigation for another diagnosis.

Scintigraphy in laryngopharyngeal and gastroesophageal reflux disease: a definitive diagnostic test?

Scintigraphic reflux studies offer a good screening tool for pharyngeal contamination and aspiration in patients with gastroesophageal reflux disease.

Laryngopharyngeal reflux: to be or not to be?

  • D. Castell
  • Medicine
    Journal of clinical gastroenterology
  • 2013
This issue of the journal, Doctors Yuksel and Vaezi have provided a comprehensive and thoughtful review of the therapeutic approaches available to the patient with possible LPR, and they provide a discussion of the evidence or lack thereof, for effective therapies for this potential condition.

Clinical and psychological characteristics in gastroesophageal reflux disease patients overlapping with laryngopharyngeal reflux symptoms

Clinical and psychological differences between GERD patients with or without LPR symptoms are investigated.

Aspiration-related pulmonary syndromes.

The broadening spectrum of aspiration-related pulmonary syndromes is discussed with a focus on presenting features and diagnostic aspects.

Laryngopharyngeal pH Monitoring in Patients With Idiopathic Pulmonary Fibrosis

Patients with IPF may have basic and acidic LPR, which may likely occur at upright and supine position, respectively, and Ryan index may not accurately reflect LPR in patients with IPf.

Laryngopharyngeal pH monitoring in patients with interstitial lung diseases

Patients with ILDs may have LPR and basic and acidic LPR may likely occur at upright and supine position, respectively, according to Ryan index, which may not accurately reflect LPR.

Quality of life, patient satisfaction, and disease burden in patients with gastroesophageal reflux disease with or without laryngopharyngeal reflux symptoms

The quality of life in patients with laryngopharyngeal reflux symptoms is also significantly impaired, however, the impact of LPR symptoms on HRQL in GERD patients has not been studied.

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The aim of this study was to estimate the burden of gastroesophageal UH?X(�GLVHDVHLQ�,UDQ� � the most common gastrointestinal tract disorders which is a threat to the quality of life.

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