Therapeutic Strategies for Autoimmune Hepatitis

  title={Therapeutic Strategies for Autoimmune Hepatitis},
  author={M. Manns and C. Strassburg},
  journal={Digestive Diseases},
  pages={411 - 415}
  • M. Manns, C. Strassburg
  • Published 2011
  • Medicine
  • Digestive Diseases
  • Autoimmune hepatitis (AIH) is a disease of unknown etiology. However, a loss of tolerance against the patient’s own liver is regarded as the main pathogenetic mechanism. Immunosuppressive therapy prolongs survival in patients with severe AIH. Two phases of therapy have to be distinguished. In newly diagnosed AIH, induction of remission is the main goal. Here predniso(lo)ne alone or in combination with azathioprine has been shown to induce remission in the majority of patients. In the past… CONTINUE READING
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