Therapeutic Mechanisms of Glucocorticoids.

Abstract

Glucocorticoids (GCs) have been used clinically for decades as potent anti-inflammatory and immunosuppressive agents. Nevertheless, their use is severely hampered by the risk of developing side effects and the occurrence of glucocorticoid resistance (GCR). Therefore, efforts to understand the complex mechanisms underlying GC function and GCR are ongoing… (More)
DOI: 10.1016/j.tem.2017.10.010

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