Therapeutic Drug Monitoring of Valproic Acid in Pediatric Epileptic Patients

Abstract

Therapeutic drug monitoring (TDM) or the measurement of drug concentrations in plasma, serum or blood, aims to improve clinical activity, avoid toxicity, and reduce the costs of drug treatment. Specific conditions for TDM to be reasonably applied include the availability of a validated assay, a considerable inter-individual pharmacokinetic variability, a… (More)

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