Therapeutic Drug Monitoring of Antiepileptic Drugs by Use of Saliva
@article{Patsalos2013TherapeuticDM, title={Therapeutic Drug Monitoring of Antiepileptic Drugs by Use of Saliva}, author={P. Patsalos and D. Berry}, journal={Therapeutic Drug Monitoring}, year={2013}, volume={35}, pages={4–29} }
Abstract:Blood (serum/plasma) antiepileptic drug (AED) therapeutic drug monitoring (TDM) has proven to be an invaluable surrogate marker for individualizing and optimizing the drug management of patients with epilepsy. Since 1989, there has been an exponential increase in AEDs with 23 currently licensed for clinical use, and recently, there has been renewed and extensive interest in the use of saliva as an alternative matrix for AED TDM. The advantages of saliva include the fact that for many… CONTINUE READING
Topics from this paper
117 Citations
Therapeutic Drug Monitoring of Antiepileptic Drugs in Epilepsy: A 2018 Update
- Medicine
- Therapeutic drug monitoring
- 2018
- 78
- PDF
Therapeutic drug monitoring of antiepileptic drugs: current status and future prospects
- Medicine
- Expert opinion on drug metabolism & toxicology
- 2020
- 4
Concentration of antiepileptic drugs in persons with epilepsy: a comparative study in serum and saliva
- Medicine
- The International journal of neuroscience
- 2016
- 14
Dried blood spots for monitoring and individualization of antiepileptic drug treatment.
- Medicine
- European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
- 2015
- 35
Dosing strategies for antiepileptic drugs: from a standard dose for all to individualised treatment by implementation of therapeutic drug monitoring.
- Medicine
- Epileptic disorders : international epilepsy journal with videotape
- 2016
- 34
- PDF
Pharmacokinetics and Drug Interaction of Antiepileptic Drugs in Children and Adolescents
- Medicine
- Pediatric Drugs
- 2018
- 10
References
SHOWING 1-10 OF 280 REFERENCES
Correlation of serum and salivary carbamazepine concentration in epileptic patients: implications for therapeutic drug monitoring.
- Medicine
- Neurology India
- 2002
- 21
- PDF
Therapeutic Drug Monitoring of the Newer Antiepileptic Drugs
- Medicine
- Therapeutic drug monitoring
- 2003
- 287
Is saliva suitable for therapeutic monitoring of anticonvulsants in children: an evaluation in the routine clinical setting.
- Medicine
- Therapeutic drug monitoring
- 1997
- 45
Possible roles for frequent salivary antiepileptic drug monitoring in the management of epilepsy
- Medicine
- Epilepsy Research
- 1990
- 35
Stability of Salivary Concentrations of the Newer Antiepileptic Drugs in the Postal System
- Medicine
- Therapeutic drug monitoring
- 2005
- 24
Saliva and Serum Levetiracetam Concentrations in Patients With Epilepsy
- Medicine
- Therapeutic drug monitoring
- 2007
- 23