Therapeutic Considerations in Treating HER2-Positive Metastatic Breast Cancer.

@article{OSullivan2014TherapeuticCI,
  title={Therapeutic Considerations in Treating HER2-Positive Metastatic Breast Cancer.},
  author={Ciara C O'Sullivan and Karen Smith},
  journal={Current breast cancer reports},
  year={2014},
  volume={6 3},
  pages={169-182}
}
Despite advances in detection and treatment, metastatic breast cancer (MBC) remains the second highest cause of cancer-related death for women in the United States. Human epidermal growth factor receptor-2 (HER2) is amplified in 25-30% of breast cancers and is associated with aggressive disease and, historically, with poorer outcomes. The advent of… CONTINUE READING