Theranostic and molecular classification of breast cancer.

  title={Theranostic and molecular classification of breast cancer.},
  author={Kristine M Cornejo and Dina Kandil and Ashraf Khan and Ediz F Cosar},
  journal={Archives of pathology & laboratory medicine},
  volume={138 1},
CONTEXT Despite advances in breast cancer management, women continue to relapse and die of breast cancer. Traditionally, evaluation for hormone receptors (estrogen and progesterone), as well as HER2 overexpression, have guided therapy-related decision-making because they are both prognostic and predictive indicators. However, there are limitations with those studies, which can lead to improper treatment. Gene signatures have recently been shown to be of value in identifying molecular portraits… CONTINUE READING
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