Theory and simulation for equilibrium glassy dynamics in cellular Potts model of confluent biological tissue.

@article{Sadhukhan2020TheoryAS,
  title={Theory and simulation for equilibrium glassy dynamics in cellular Potts model of confluent biological tissue.},
  author={Souvik Sadhukhan and Saroj Kumar Nandi},
  journal={Physical review. E},
  year={2020},
  volume={103 6-1},
  pages={
          062403
        }
}
Glassy dynamics in a confluent monolayer is indispensable in morphogenesis, wound healing, bronchial asthma, and many others; a detailed theoretical framework for such a system is, therefore, important. Vertex-model (VM) simulations have provided crucial insights into the dynamics of such systems, but their nonequilibrium nature makes theoretical development difficult. The cellular Potts model (CPM) of confluent monolayers provides an alternative model for such systems with a well-defined… 

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References

SHOWING 1-10 OF 19 REFERENCES

Develop

Front

  • Philip D. Plowright
  • 2020 Fourth World Conference on Smart Trends in Systems, Security and Sustainability (WorldS4)
  • 2020

arXiv

The innovative preprint repository, arXiv, was created in the early 1990s to improve access to scientific research. arXiv contains millions of Open Access articles in physics, mathematics, computer

I and J

Structural Glasses and Supercooled Liquids: Theory, Experiment, and Applications

Preface vii Contributors xi 1 Supercooled Liquid Dynamics: Advances and Challenges 1 Ranko Richert 2 The Random First-Order Transition Theory of Glasses: A Critical Assessment 31 Giulio Biroli and

The Cellular Potts Model and Biophysical Properties of Cells, Tissues and Morphogenesis

The properties of the Cellular Potts Model (CPM) formalism are examined, which show that the modelling formalism is a powerful tool for investigating a large range of biological questions, from those concerning biophysical properties of single cells, cell motion, tissue level properties, all the way up to understanding the full morphogenesis and life-cycle of an organism.

Cell Adhesion and Migration 10

  • 1
  • 2016

Rheol

  • Acta. 52, 425
  • 2013

Solids 407

  • 14
  • 2015

PLoS Comp

  • Biol. 15, e1007459
  • 2019